
Advancing Human-Aligned Technology
What we do
Our Focus Areas
Invest in AI Security
Fund early-stage builders developing tools that enable model interpretability, trustworthy agents, hardware security.
Advance AGI/ASI Alignment
Back practical research and tractable methods to address existential and catastrophic risk of AGI/ASI.
Strengthen AI Assurance
Support development of tools and techniques to enable evaluation, compliance, reliability, and human control.
Enable Smart Governance
Facilitate development of tools and governance innovations that enhance security, trust and human agency.
Promote Global Cooperation
Convene multistakeholder and Track II diplomacy to address shared international security concerns.
Empower Civil Society
Invest in privacy-preserving tools that protect human rights and capacity building for AI governance innovation.

“Compatible” + “Sympathetic” + “Like-minded”
What we support
Investments, Grants, & Partners
We invest in mission-aligned companies and venture funds. We also make grants to support technical research, policy innovation, and international cooperation.
Archia
Trustworthy agents and private use of frontier models
AVERI
3rd party auditing and evaluation of frontier models.
Local Host Research
Bitcoin codebase resilience and infrastructure support.
AI Security Connect
International AI security diplomacy and governance.
Global Network Initiative - MAP AI Project
Rights-protecting AI policy and multistakholder governance.
Who we are
Leadership
Sympatico Ventures founder and managing partner Eileen Donahoe is a former US technology diplomat, international lawyer, and human rights advocate.
She’s been deeply engaged in digital policy and global multistakeholder technology governance for several decades, including as U.S. Special Envoy and Coordinator for Digital Freedom in the Biden administration, as U.S. Ambassador to the United Nations Human Rights Council in the Obama administration, and as co-founder of the Global Digital Policy Incubator at Stanford University.
At this juncture, with the benefit of having lived in Silicon Valley for the past 40 years, Eileen is excited to help seed the field of AI-alignment and support entrepreneurs building tools that enhance human agency, liberty, security, and trust.
Advisors supporting Sympatico's mission:
Our work is being advanced by a combination of inspired leaders in the field.

April Chou
Managing Director Philanthropy & Impact Investing Jasper Ridge Partners
About us
Underlying Rationale
“Advanced AI must enhance human agency—not undermine it.”

Eileen Donahoe
Founder, Managing Partner




